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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMF1
All Species:
40.61
Human Site:
S573
Identified Species:
55.83
UniProt:
P82094
Number Species:
16
Phosphosite Substitution
Charge Score:
0.19
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P82094
NP_009045.2
1093
122842
S573
S
K
Q
Q
L
H
N
S
N
I
I
K
K
L
R
Chimpanzee
Pan troglodytes
XP_526227
1093
122795
S573
S
K
Q
Q
L
H
N
S
N
I
I
K
K
L
R
Rhesus Macaque
Macaca mulatta
XP_001088711
1092
122828
S572
S
K
Q
Q
L
H
N
S
N
I
I
K
K
L
R
Dog
Lupus familis
XP_533766
1089
122761
S570
S
K
Q
Q
L
H
N
S
N
I
I
K
K
L
R
Cat
Felis silvestris
Mouse
Mus musculus
B9EKI3
1091
121796
S571
S
K
Q
Q
L
H
N
S
N
I
I
K
K
L
R
Rat
Rattus norvegicus
NP_446123
1093
121882
S573
S
K
Q
Q
L
H
N
S
N
M
I
K
K
L
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510334
1106
124384
S580
S
K
Q
Q
L
H
N
S
N
I
I
K
K
L
R
Chicken
Gallus gallus
O42184
1433
161009
L766
S
E
E
K
L
L
D
L
A
A
L
Q
K
A
N
Frog
Xenopus laevis
Q5PQ23
649
75475
E204
L
Q
K
Q
Q
L
Q
E
E
K
A
H
L
L
A
Zebra Danio
Brachydanio rerio
NP_001003522
1136
126986
S608
S
K
Q
Q
L
Q
H
S
N
I
I
K
K
L
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572360
933
103794
A487
E
A
V
C
R
M
T
A
E
K
K
R
V
D
E
Honey Bee
Apis mellifera
XP_394037
1326
150590
T648
I
E
A
E
I
Q
G
T
E
M
P
R
E
N
S
Nematode Worm
Caenorhab. elegans
P02566
1966
225108
E1198
E
E
A
N
M
N
H
E
N
Q
L
G
G
L
R
Sea Urchin
Strong. purpuratus
XP_785821
1176
131318
S653
S
K
Q
Q
L
Q
N
S
N
V
I
K
K
L
R
Poplar Tree
Populus trichocarpa
XP_002303293
975
109171
S530
E
K
H
Q
A
E
L
S
A
Q
K
I
Y
Y
T
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q0WVL7
956
108335
T511
T
E
K
L
L
Q
E
T
I
E
K
H
Q
A
E
Baker's Yeast
Sacchar. cerevisiae
P47166
707
81153
D262
E
K
N
I
K
E
K
D
D
L
I
T
I
L
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
98.5
93.1
N.A.
87.2
86.7
N.A.
81.2
21.7
22.6
59.7
N.A.
26.1
23.9
21
37.7
Protein Similarity:
100
99.4
99.1
96.1
N.A.
92.5
92
N.A.
88.3
39.9
37.3
74.6
N.A.
45.8
44.9
36.6
56.8
P-Site Identity:
100
100
100
100
N.A.
100
93.3
N.A.
100
20
13.3
86.6
N.A.
0
0
20
86.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
60
26.6
93.3
N.A.
13.3
46.6
53.3
93.3
Percent
Protein Identity:
25.8
N.A.
N.A.
27.1
21.1
N.A.
Protein Similarity:
47.2
N.A.
N.A.
45.4
39.4
N.A.
P-Site Identity:
20
N.A.
N.A.
6.6
20
N.A.
P-Site Similarity:
20
N.A.
N.A.
40
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
6
12
0
6
0
0
6
12
6
6
0
0
12
6
% A
% Cys:
0
0
0
6
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
6
6
6
0
0
0
0
6
0
% D
% Glu:
24
24
6
6
0
12
6
12
18
6
0
0
6
0
12
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
6
0
0
0
0
6
6
0
0
% G
% His:
0
0
6
0
0
42
12
0
0
0
0
12
0
0
0
% H
% Ile:
6
0
0
6
6
0
0
0
6
42
59
6
6
0
0
% I
% Lys:
0
65
12
6
6
0
6
0
0
12
18
53
59
0
0
% K
% Leu:
6
0
0
6
65
12
6
6
0
6
12
0
6
71
0
% L
% Met:
0
0
0
0
6
6
0
0
0
12
0
0
0
0
0
% M
% Asn:
0
0
6
6
0
6
48
0
59
0
0
0
0
6
6
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
6
0
0
0
0
% P
% Gln:
0
6
53
65
6
24
6
0
0
12
0
6
6
0
6
% Q
% Arg:
0
0
0
0
6
0
0
0
0
0
0
12
0
0
59
% R
% Ser:
59
0
0
0
0
0
0
59
0
0
0
0
0
0
6
% S
% Thr:
6
0
0
0
0
0
6
12
0
0
0
6
0
0
6
% T
% Val:
0
0
6
0
0
0
0
0
0
6
0
0
6
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
6
6
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _